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- W2386242008 abstract "Objective To develop a near infrared diffuse reflectance spectroscopy method for rapid determination of moisture content in cefprozil APIs.Methods The near infrared diffuse reflectance spectroscopy of cefprozil APIs which were measured by Karl Fischer titration as reference result were measured by a fiber optic probe.The calibration model between the spectra data and the reference result was developed by partial least squares regression.Results As the concentration range was 0.7%～9.8%,The regression coefficient(r) was 0.999 6,the root mean square error of cross validation(RMSECV) was 0.40 and the root mean square error of prediction(RMSEP) was 0.41.Conclusions The model has a good performance for prediction.It provides a fast and easy detection method to control the quality of cefprozil APIs." @default.
- W2386242008 created "2016-06-24" @default.
- W2386242008 creator A5053613555 @default.
- W2386242008 date "2012-01-01" @default.
- W2386242008 modified "2023-09-23" @default.
- W2386242008 title "Rapid and nondestructive determination of moisture content in cefprozil APIs by near infrared spectroscopy" @default.
- W2386242008 hasPublicationYear "2012" @default.
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