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- W2386278945 abstract "Objective To compare the values of endobronchial ultrasound guided transbronchial needle aspiration(EBUS-TBNA) and positron-emission tomography and computed tomography(PET/CT) in diagnosis of enlarged mediastinal lymph nodes caused by unknown reasons,and to study the diagnostic value of the combination of EBUS-TBNA and PET/CT.Methods A retrospective study was carried out in our hospital.From December 2010 to August 2011,a total of 45 patients with enlarged mediastinal lymph nodes received EBUS-TBNA following PET/CT examination.Conventional bronchoscopy was performed before EBUS-TBNA.The patients with endobronchial lesions were excluded from this study.Patients with negative EBUS-TBNA results underwent surgical biopsies or a minimum of 6 months' clinical and radiological follow-up.Results Sensitivities of EBUS-TBNA and PET/CT in diagnosis of enlarged mediastinal lymph nodes were 81.48%(22/27) and 92.59%(25/27),the specificities were 100%(18/18) and 55.56%(10/18),the positive predictive values(PPV) were 100%(22/22) and 75.76%(25/33),the negative predictive values(NPV) were 78.26%(18/23) and 83.33%(10/12),the accuracies were 88.89%(40/45) and 77.78%(34/45),respectively.EBUS-TBNA had a significantly better specificity(P=0.003) and PPV(P=0.016) than PET/CT for diagnosis of enlarge mediastinal lymph nodes.Conclusion EBUS-TBNA is valuable for diagnosing enlarged mediastinal lymph nodes caused by unknown reasons.EBUS-TBNA combined with PET/CT can reduce the false negative results in diagnosis of malignant mediastinal lymph nodes." @default.
- W2386278945 created "2016-06-24" @default.
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- W2386278945 date "2012-01-01" @default.
- W2386278945 modified "2023-09-24" @default.
- W2386278945 title "Application of EBUS-TBNA and PET/CT in diagnosing enlarged mediastinal lymph nodes caused by unknown reasons" @default.
- W2386278945 hasPublicationYear "2012" @default.
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