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- W2386286222 abstract "Objective To evaluate effects of ectogenous epidermal growth factor (EGF) on postoperative inflammation and epithelial healing after LASEK.Methods Fifty-eight myopia patients (including both eyes of each patient) were topically treated with recombinant human epidermal growth factor (rhEGF) +0.1% fluorometholone+0.3% of loxacin after treatment with LASEK. Sixty patients with the same surgery were treated as control where treatment of 0.1% fluorometholone+0.3% of loxacin was topically used. Clinical observation on the eyes was followed at 1, 2, 3 and 5 days postoperatively. Visual acuity was measured at 1, 2 and 3 weeks postoperatively. Corneal haze was assessed at 1, 2 and 3 months postoperatively. A total score was used to record all adverse responses of each eye.Results The average score for the EGF group was 7.02±3.33 at day 1 and 4.98±3.30 at day 2. The average score for the control group was 8.28±3.77 at day 1 and 6.45±3.75 at day 2. The overall average score in the EGF group was significantly lower than in the control group (P0.05). There was no difference in rapidity of achieving best uncorrected visual acuity between the two groups. The number of eyes with corneal haze were 28 eyes for the EGF group and 31 eyes for the control group. The severity of corneal haze was lower than 0.5 score for the two groups.Conclusion rhEGF may relieve early inflammation after LASEK and is safe and beneficial to the epithelial healing after the surgery." @default.
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- W2386286222 date "2007-01-01" @default.
- W2386286222 modified "2023-09-23" @default.
- W2386286222 title "Effects of epidermal growth factor (EGF) on postoperative inflammation and epithelial healing after LASEK" @default.
- W2386286222 hasPublicationYear "2007" @default.
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