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- W2386288587 abstract "Objective The aim of this study was to evaluate the effect of losartan on endothelial function in patients with diabetic foot.Methods Sixty patients with diabetic foot and a wide variation of endothelial dysfunction were randomly divided into two groups.Group A received losartan,group B received diuretic drugs,alpha or beta-blockers.Endothelial function was measured before and 16 weeks after treatment.Results After the treatment,endothelial-dependent dilation(EDD)(5.45%±1.19% vs 7.11%±1.62%) and endothelial-independent dilation(EID)(14.12%±1.58% vs 16.03%±1.51%) in the group A patients were significantly(P0.05) increased.For the group B patients,EDD and EID was the same before and after the treatment(P0.05).Conclusion Losartan can significantly improve endothelial function in patients with diabetic foot.It is also safe and has a good tolerability profile." @default.
- W2386288587 created "2016-06-24" @default.
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- W2386288587 date "2011-01-01" @default.
- W2386288587 modified "2023-09-23" @default.
- W2386288587 title "Effect of losartan on endothelial function of patients with diatetic foot" @default.
- W2386288587 hasPublicationYear "2011" @default.
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