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- W2386339201 abstract "Objective To analyze characteristics of atherosclerotic plaques in coronary heart disease(CHD) patients with diabetic mellitus(DM) by intravascular ultrasound-virtual histology(IVUS-VH) and to discuss their correlations with glycated serum album(GA) and glycated hemoglobin(HbA1c).Methods In 53 CHD patients with DM and 49 CHD patients,culprit lesions were detected with IVUS-VH to investigate characteristics of atherosclerotic plaques and their relevance with GA and HbA1c.Results CHD patients with DM presented a significantly higher prevalence of vulnerable plaques than CHD patients(6.7%:14.5%,P 0.05),with a clear clustering pattern,mainly consisting of fibro-fatty tissues and necrotic core-rich tissues.There were higher levels of fibrous tissues and dense calcium tissues in CHD patients compared with CHD patients with DM.There was a positive relevance of fibro-fatty tissue with GA(r=0.018,P0.05),which was much higher than that with HbA1c.Conclusion As shown by IVUS-VH,the prevalence of vulnerable plaques in CHD patients with DM is much higher than that of CHD patients,coupled with different intra-plaque compositions,which is associated with the GA level." @default.
- W2386339201 created "2016-06-24" @default.
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- W2386339201 date "2011-01-01" @default.
- W2386339201 modified "2023-09-28" @default.
- W2386339201 title "Relation of glycated serum album and vulnerable plaque characteristics in patients with CHD" @default.
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