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- W2386360933 abstract "Objective:To evaluate the efficacy of propofol TCI guided by the bispectral index on stress responses to tracheal intubation in elderly patients with radical gastrectomy.Methods:Sixty patients over 70 year-old undergoing radical gastrectomy for stomach cancer were randomized to receive a BIS-guided propofol TCI anesthetic regimen or standard clicical practice.All patients were induced with step-by-step propofol TCI.In group B,tracheal intubation was performed when anesthesia was adjusted to achieve a BIS level 45-55.In group S,tracheal intubation was performed when standard criteria was achieved.SBP,DBP,HR and BIS were recorded before induction(T0),loss of consciousness(T1),intubation(T2),at 1 min(T3),3 min(T4)and 5 min(T5)after intubation.Effect concentration and dose of propofol were recorded during intubation.Results:Within-group changes,SBP,DBP and HR decreased at T1,T2,and increased at T3,T4.SBP,DBP were lower at T2 than those at T0(P0.05).SBP,DBP were higher at T3,T4 than those at T2(P0.05).Compared with group S,SBP,DBP,HR were significantly increased at T3,T4(P0.05).Conclusion:During anesthesia induction propofol TCI guided by the BIS attenuated the increase in both arterial pressure and heart rate after tracheal intubation.Anesthesia induction by TCI of propofol,the BIS values between 46 to 55 may attenuate the stress responses to tracheal intubation." @default.
- W2386360933 created "2016-06-24" @default.
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- W2386360933 date "2009-01-01" @default.
- W2386360933 modified "2023-09-23" @default.
- W2386360933 title "Assessment of propofol TCI for anesthesia induction guided by the bispectral index in elderly patients with radical gastrectomy" @default.
- W2386360933 hasPublicationYear "2009" @default.
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