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- W2386362246 abstract "Objective To explore the effects of ascorbic acid on the content of MDA,activity of SOD and content of GSH in arsenic poisoning mice.Methods The malonaldehyde(MDA) content was detected by thio-barbituric acid me-thod.Superoxide dismutase(SOD) activity was determined by nitrite-kit.Glutathione(GSH) content was detected by dinitrothiocyanobenzene chromatometry.Results The content of MDA in control group was 14.87 nmol/mg·prot;SOD activity was 167.49 NU/mg·prot;GSH content was 51.27 nmol/mg·prot.In 20μmol/L arsenite treated group,the MDA increased to 18.48 nmol/mg·prot;SOD activity decreased to 125.97NU/mg·prot;and GSH content decreased to 34.87 nmol/mg·prot.In the ascorbic acid treated group,the MDA content decreased to 16.24nmol/mg·prot;SOD activity increased to 138.94 NU/mg·prot;GSH content increased to 50.39 nmol/mg·prot.Conclusion Ascorbic acid can alleviate the oxidative damage induced by arsenic in mice liver." @default.
- W2386362246 created "2016-06-24" @default.
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- W2386362246 date "2009-01-01" @default.
- W2386362246 modified "2023-09-23" @default.
- W2386362246 title "Antagonistic effect of ascorbic acid on oxidative damage induced by arsenic in mice" @default.
- W2386362246 hasPublicationYear "2009" @default.
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