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- W2386367046 abstract "Objective:To study the inhibitory effect of TAM or MA single,and TAM/MA sequential or combination on cultured human breast cancer cell line (Bcap 37 cell line)in vitro,in order to guide us on selecting the best regimen of TAM MA sequential or combination.Methods:Three regimens of TAM/MA combination therapy and single drug(TAM or MA)were designed and their inhibitory effects to human breast cancer cell line (Bcap 37 cell line) in vitro(MTT assay)were observed.Results:(1)The inhibition of TAM and MA single to Bcap 37 cell is similar in low concentration(0.25 mg/L to 2.5 mg/L).From 2.5 mg/L to 7.5 mg/L,the inhibitory effects of TAM was greater than that of MA significantly( P 0.05).(2)The inhibitory effect of TAM→MA sequential was greater than the MA→TAM sequential or TAM+MA combination in all concentration( P 0.05).In low concentration,the inhibition of TAM+MA and MA→TAM sequential was similar,but in high concentration,the former became greater remarkably( P =0.05 and P 0.05,respectively).Conclusion:In the TAM and MA combination therapy regimens,the TAM→MA sequential or the TAM/MA combination therapy is the best choice." @default.
- W2386367046 created "2016-06-24" @default.
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- W2386367046 date "2000-01-01" @default.
- W2386367046 modified "2023-10-03" @default.
- W2386367046 title "STUDIES ON INHIBITORY EFFECT OF TAM AND MA SEQUENTIAL OR COMBINATION ON CULTURED HUMAN BREAST CANCER BCAP 37 CELL IN VITRO" @default.
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