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- W2386392018 abstract "Objective To compare the ability of dual energy CT pulmonary angiography imaging(CTPA),dual energy CT perfusion imaging(DEPI) and MRI(combined MRPA and MR pulmonary perfusion)to detect pulmonary embolism(PE) in rabbit models.Materials and Methods Experimental rabbit models of acute PE were established by injecting four gelatin sponge emboli into femoral vein.Dual energy CT(DECT) and 3T MRI were performed at 2 hours after embolisation.Images of dual energy CTPA,DEPI,and MRPA and MRPP were obtained.The location and number of the emboli in per lobe were recorded.The pathology results were regarded as the reference standards.Sensitivity,specificity and agreement of the above-mentioned methods were calculated.Results The sensitivity and specificity of CTPA and DEPI were 95.8%,95.8% and 94.1%,90.2%,respectively.The sensitivity and specificity of MRI was 83.3% and 90.2%.Excellent inter modality agreement was obtained between CTPA and DEPI(Kappa value=0.971,P0.001).Good inter modality agreement was obtained between DECT and MRI(Kappa value=0.796,P0.001).There was no significant difference between DECT and MRI(P0.05).DEPI had a higher accuracy(92%) than MRPP(78.7%)(P0.001).Conclu-sion DECT had a slightly high sensitivity than MRPA with no statistically significance.DEPI had a higher accuracy than MRPP to visualize perfusion defect derived from pulmonary emboli in rabbit model." @default.
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- W2386392018 date "2011-01-01" @default.
- W2386392018 modified "2023-09-23" @default.
- W2386392018 title "Experimental Acute Pulmonary Embolism in Rabbits:Correlation of Dual energy CT and MR Angiography at 3T" @default.
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