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- W2386550413 abstract "Objective To investigate the clinical significance of the expressions of E-cad and PCNA in bladder tumor. Methods Immunohistochemical study for E-cad and PCNA from 1995 to 2010 were performed on 76 cases of paraffin-embedded specimens of surgical carcinoma and 12 cases of mastoid tumor, the E-cad abnormal expression rate of cancer cells in slice of every patients and proliferating cell nuclear antigen positive index(PLI) were calculated. Results There were significant difference in E-cad and PCNA between the transitional cell carcinoma of bladder (84.2%) and mastoid tumor (16.7%). The positive expression of PCNA was significantly increased with stage and grade (P 0.05), the PLI were (35.85±8.20)% and (80.24±19.52)% in the transitional cell carcinoma of bladder and mastoid tumor, difference had statisticod significance (P 0.05). But the positive expression of E-cad decreased with the stage and grade (P 0.05). Conclusion E-cad has correlation with infiltration and transfer of bladder malignant tumor, the expression of E-cad and PCNA can be used to estimate the metastatic potenciality and help for the adguvant treatment." @default.
- W2386550413 created "2016-06-24" @default.
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- W2386550413 date "2012-01-01" @default.
- W2386550413 modified "2023-09-27" @default.
- W2386550413 title "Expression and significance of E-cadherin (E-cad) and proliferating cell nuclear antigen (PCNA) in bladder tumor" @default.
- W2386550413 hasPublicationYear "2012" @default.
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