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- W2386593467 abstract "Purpose In this article, a case who was prescribed duloxetine (30 mg capsule) upon the fibromyalgia diagnosis by a physical therapist and had acute dystonia and dyskinesia after approximately 1.5 hours from duloxetine intake shall be presented. Case It was learnt that a married female patient aged 38 consulted a physical therapist with the complaint of back pain and duloxetine (30 mg capsule) was prescribed. It was reported that, the patient applied to our hospital with the compliant of involuntary movements around the mouth, on the lips and neck, spasm, inability to open the mouth completely, spasm in jaw, gritting teeth, mumbling and aphasia after approximately 1.5 hours from her duloxetine intake. The patient was conscious. Her psychomotor activity was natural. As a result of cranial MR, EEG, BT examinations hemogram and the routine biochemistry examinations, any abnormality in zinc and iron levels was not detected. Complaints of the patient regressed after 1 hour from the discontinuance of duloxetine and the administration of biperiden 5 mg/mL ampoule 1000 cm 3 in SF. After 72 hours, any symptoms were not found. Discussion Dopamine neurotransmission can be inhibited through the increase in serotonin and norepinephrine. Additionally, dystonia may originate from the prevailing of noradrenaline as a result of the failure of dopaminergic–noradrenergic balance. Disclosure of interest The author has not supplied his/her declaration of competing interest." @default.
- W2386593467 created "2016-06-24" @default.
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- W2386593467 date "2016-03-01" @default.
- W2386593467 modified "2023-10-18" @default.
- W2386593467 title "Acute dystonia and dyskinesia progressing in the patient with fibromyalgia upon the use of duloxetine" @default.
- W2386593467 cites W1996673522 @default.
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- W2386593467 doi "https://doi.org/10.1016/j.eurpsy.2016.01.2321" @default.
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