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- W2386608889 abstract "Objective To study the expression and the relationship between platelet-derived growth factor B chain(PDGF-BB) and vascular endothelial growth factor(VEGF) in angioreticuloma.Methods Examing and analyzing the expressions of PDGF-BB and VEGF in 32 cases of angioreticuloma and 10 cases of normal brain tissue by adopting streptavidin-peroxidase(SP) immunohistochemical technique.Results There were significant differences in the expressions of PDGF-BB and VEGF between angioreticuloma and normal brain tissue with the gray values of PDGF-BB 101.2±15.7 vs 180.2±14.6 and those of VEGF 104.4±15.8 vs 181.5±14.6(all P0.01).The expressions of PDGF-BB and VEGF were positively correlated(r=0.842,P0.01).Conclusion Angioreticuloma can secrete PDGF-BB and VEGF.There can be a very close correlation in effecting mechanics between PDGF-BB and VEGF. Examing PDGF-BB and VEGF can provide a new method for studying the desease and its clinical mechanics.Anti-PDGF-BB and anti-VEGF therapies may provide a new method for curing angioreticuloma." @default.
- W2386608889 created "2016-06-24" @default.
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- W2386608889 date "2009-01-01" @default.
- W2386608889 modified "2023-09-24" @default.
- W2386608889 title "Clinical role and expression of platelet-derived growth factor B chain and vascular endothelial growth factor in angioreticuloma" @default.
- W2386608889 hasPublicationYear "2009" @default.
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