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- W2386616071 abstract "Objective To detect the relationship between genetic polymorphism of beta-3 adrenergic-receptor gene and type 2 Diabetic and Essential Hypertension.Methods Polymorphism of the 190th site T/C of β3-ARgene was detected by PCR-restretion fragment length polymorphism in patients with Type 2 Diabetic(n=74),patients with Essential Hypertension(n=82) and normal controls(n=108).Results The 190th site of β3-ARgene the frequencies of TT,TC and CC genotype was 68.92%,17.57% and 13.51%in patients with Type 2 Diabetic,while 82.93%,13.41% and 3.66% in patients with Essential Hypertension and 84.26%,12.96% and 2.78% in normal controls.There is a significant difference between groups of patients with Type 2 Diabetic and patients with Essential Hypertension,patients with Type 2 Diabetic and normal controls.No significant was seen in patients with Essential Hypertension and normal controls.Conclusion The distribution frequency of β3-ARgene has something to do with morbility of Type 2 Diabetic but has nothing to do with morbility of Essential Hypertension.Genotypes T/T inβ3-ARgene may have a protective effect against Type 2 Diabetic." @default.
- W2386616071 created "2016-06-24" @default.
- W2386616071 creator A5025979085 @default.
- W2386616071 date "2013-01-01" @default.
- W2386616071 modified "2023-09-22" @default.
- W2386616071 title "Relationship between genetic polymorphism of beta-3-adrenergic-receptor gene and type 2 Diabetic and Essential Hypertension" @default.
- W2386616071 hasPublicationYear "2013" @default.
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