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- W2386661330 abstract "Objective:To investigate the effects of EDC cross-linking on the physicochemical properties of ionized collagen scaffolds.Methods:Ionized collagen scaffolds:native collagen(NC),methylation collagen(MC)and succinylated collagen(SC),were fabricated with modification of side chain and 1-ethyl-3-(3- dimethyl-aminopropyl)carbodiimide(EDC)cross-linking.Scaffolds were observed and analyzed using scanning electron microscopy(SEM),differential scanning calorimeter(DSC),Fourier transform infrared radiometer(FT-IR)and experiment of enzyme degradation in vitro.And the effects of EDC cross-linking on the physicochemical properties of collagen scaffolds were investigated.Results:The results indicated that modification of side chain had changed the surface charge of collagen,and EDC cross-linking had improved pore size,porosity,denatured temperature(Td)and ability of antienzyme degradation of NC and MC,changed chemical structure of NC and MC;but that had no influences on pore size,porosity,chemical structure of SC,and decreased Td and ability of antienzyme degradation of it.Coclusion:These data indicate that EDC cross-linking may lead to enhanced physicochemical properties of ionized collagen scaffolds.It provided experimental basis of ionized collagen using in periodontal tissue engineering scaffolds." @default.
- W2386661330 created "2016-06-24" @default.
- W2386661330 creator A5054427114 @default.
- W2386661330 date "2015-01-01" @default.
- W2386661330 modified "2023-09-23" @default.
- W2386661330 title "Biological Characterization of Ionized Collagen Scaffolds with EDC Cross-linking." @default.
- W2386661330 hasPublicationYear "2015" @default.
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