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- W2386670981 abstract "Objective To evaluate efficiency of serial MRI on observing development of experimental syringomyelia in rabbits. Methods Thirty-two New Zealand rabbits (Kaolin group 16 rabbits, physiological saline group 8 rabbits and shamed-operation group 8 rabbits) were used in this study. Kaolin solution was injected into the cisterna magna of the first group animals to produce syringomyelia models and the other two were designed as controls. MR imaging was performed at a regular intervel in all rabbits to compared with the findings of light microscopy. Results At 2 weeks after operation, MRI revealed ischemic and edematous changes in upper cervical cord in 11 of the remained 14 rabbits. At 4-6 weeks, (10/11) 90% animals in Kaolin group developed syringomyelia. Syringomyelia enlarged gradually with time and the number of involved segments increased. Histological results coincided with the MRI findings. Conclusion MRI, coincided with light microscopy, can wholly and correctly observe the development of experimental syringomyelia in rabbits." @default.
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- W2386670981 date "2007-01-01" @default.
- W2386670981 modified "2023-09-23" @default.
- W2386670981 title "Value of serial MRI observing development of experimental syringomyelia in rabbits" @default.
- W2386670981 hasPublicationYear "2007" @default.
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