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- W2386724622 abstract "Most of the data on the induction of major histocompatibility complex (MHC) restrictions are derived from studies of helper, proliferating, and cytolytic T cells. In this report we investigated the mechanisms responsible for the induction of I-J restrictions in suppressor T cells (Ts). Three distinct Ts subpopulations have been identified in the 4-hydroxy-3-nitrophenyl acetyl (NP) system (1–3). These were termed Ts1, Ts2 and Ts3 cells, respectively. Ts1 cells or their soluble factors do not display any H-2 restriction (4). In contrast, Ts2 and Ts3 cells and their factors are genetically restricted by genes in the I-J subregion (2). This report focuses on the induction of Ts3 cells. Ts3 cells are present in conventionally primed mice, but they only exert their suppressive activity following activation by Ts2 cells or factors derived from Ts2 cells (1, 3, 5)." @default.
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- W2386724622 date "1983-01-01" @default.
- W2386724622 modified "2023-09-26" @default.
- W2386724622 title "Induction of I-J Restrictions on Suppressor Cells" @default.
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- W2386724622 doi "https://doi.org/10.1007/978-1-4612-5633-5_72" @default.
- W2386724622 hasPublicationYear "1983" @default.
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