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- W2386724904 abstract "Chronic obstructive pulmonary disease( COPD) is a prevalent disease which is the fourth leading cause of death worldwide and will be the major economic burden of diseases according to the World Bank / World Health Organization. However,the pathogenesis of COPD is inadequately understood,oxidative stress and chronic inflammation are considered to be two independent pathogenetic factors,but the epigenetic put them together because of changes of the environment lead to gene abnormal expression. This article summarizes the relationship between histone modifications of genes induced by oxidative stress and the inflammation,antioxidant response,apoptosis,autophagy and the differentiation of T cell subsets in the pathogenesis of COPD. The work will provide more choices for clinical treatment of COPD." @default.
- W2386724904 created "2016-06-24" @default.
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- W2386724904 date "2014-01-01" @default.
- W2386724904 modified "2023-09-28" @default.
- W2386724904 title "The role of oxidative stress induced histone modification in chronic obstructive pulmonary disease" @default.
- W2386724904 hasPublicationYear "2014" @default.
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