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- W2386750898 abstract "Objective:To investigate the inhibitive effect of cytotoxic T lymphocytes(CTLs),actived by dendritic cells(DCs),associated with 5-fluorouracil(5-FU) on carcinoma cervicis in vitro and in nude mice.Methods:The inhibitive effect of CTLs,actived by DCs,associated with 5-FU on carcinoma cervicis was detested in vitro by MTT methods.Additionally,there were four groups in experiments of nude mice:control,CTLs,5-FU and CTLs/5-FU groups.These treatements given before or after the mice were attacked by carcinoma cervicis cells and the tumor generating rate,the latent phase,the volume and weight of tumor were observed.Results:The inhibitive effect of three therapy groups was significantly increased,especially the CTLs/5-FU group in vitro(P0.01).Additionally,in vivo,the latent phase of therapy groups increased and the tumor generating rate,the volume and weight of tumor decreased too,especially the CTLs/5-FU group(P0.01).Conclusion:CTLs,actived by DCs,associated with 5-FU are more effective to carcinoma cervicis than CTLs or 5-FU." @default.
- W2386750898 created "2016-06-24" @default.
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- W2386750898 date "2008-01-01" @default.
- W2386750898 modified "2023-09-25" @default.
- W2386750898 title "Inhibitive effect of CTLs,actived by dendritic cells,associated with 5-FU on carcinoma cervicis in vitro and in nude mice" @default.
- W2386750898 hasPublicationYear "2008" @default.
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