Matches in SemOpenAlex for { <https://semopenalex.org/work/W2386887887> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2386887887 abstract "Objective To investigate the effects of baicalein on the fibrillation and cytotoxicity of amyloid β-protein Aβ1-42.Methods The inhibitory effects of baicalein on Aβ1-42 fibril formation were determined by using thioflavin T fluorescence(Th-T).The protective effects against cytotoxicity induced by Aβ1-42 in PC12 cells were evaluated by MTT assay.Results The data from Th-T fluorescence assay showed that baicalein had a dose-dependent effect on inhibition of Aβ1-42 fibril formation and disaggregation of pre-formed Aβ1-42 fibril.It also reduced the neurotoxicity of Aβ1-42 on the cultured PC12 cells in(P0.01),as determined by the MTT method.Conclusion These findings provide evidence that baicalein can effectively inhibit Aβ1-42 fibril formation and aggregation and significantly lower the neurotoxicity on PC12 cell line,suggesting that baicalein may be a candidate for prevention or treatment of Alzheimer's disease." @default.
- W2386887887 created "2016-06-24" @default.
- W2386887887 creator A5016614062 @default.
- W2386887887 date "2013-01-01" @default.
- W2386887887 modified "2023-09-26" @default.
- W2386887887 title "Effects of Baicalein on the Fibrillation and Cytotoxicity of Amyloid β-Peptide" @default.
- W2386887887 hasPublicationYear "2013" @default.
- W2386887887 type Work @default.
- W2386887887 sameAs 2386887887 @default.
- W2386887887 citedByCount "0" @default.
- W2386887887 crossrefType "journal-article" @default.
- W2386887887 hasAuthorship W2386887887A5016614062 @default.
- W2386887887 hasConcept C109316439 @default.
- W2386887887 hasConcept C126322002 @default.
- W2386887887 hasConcept C142724271 @default.
- W2386887887 hasConcept C153911025 @default.
- W2386887887 hasConcept C178790620 @default.
- W2386887887 hasConcept C179104552 @default.
- W2386887887 hasConcept C185592680 @default.
- W2386887887 hasConcept C202751555 @default.
- W2386887887 hasConcept C27523624 @default.
- W2386887887 hasConcept C2777356233 @default.
- W2386887887 hasConcept C2777633098 @default.
- W2386887887 hasConcept C2778896982 @default.
- W2386887887 hasConcept C2779134260 @default.
- W2386887887 hasConcept C2779161974 @default.
- W2386887887 hasConcept C2779281246 @default.
- W2386887887 hasConcept C2779491297 @default.
- W2386887887 hasConcept C2780783641 @default.
- W2386887887 hasConcept C2781466915 @default.
- W2386887887 hasConcept C29730261 @default.
- W2386887887 hasConcept C502032728 @default.
- W2386887887 hasConcept C55493867 @default.
- W2386887887 hasConcept C71924100 @default.
- W2386887887 hasConcept C86803240 @default.
- W2386887887 hasConcept C98274493 @default.
- W2386887887 hasConceptScore W2386887887C109316439 @default.
- W2386887887 hasConceptScore W2386887887C126322002 @default.
- W2386887887 hasConceptScore W2386887887C142724271 @default.
- W2386887887 hasConceptScore W2386887887C153911025 @default.
- W2386887887 hasConceptScore W2386887887C178790620 @default.
- W2386887887 hasConceptScore W2386887887C179104552 @default.
- W2386887887 hasConceptScore W2386887887C185592680 @default.
- W2386887887 hasConceptScore W2386887887C202751555 @default.
- W2386887887 hasConceptScore W2386887887C27523624 @default.
- W2386887887 hasConceptScore W2386887887C2777356233 @default.
- W2386887887 hasConceptScore W2386887887C2777633098 @default.
- W2386887887 hasConceptScore W2386887887C2778896982 @default.
- W2386887887 hasConceptScore W2386887887C2779134260 @default.
- W2386887887 hasConceptScore W2386887887C2779161974 @default.
- W2386887887 hasConceptScore W2386887887C2779281246 @default.
- W2386887887 hasConceptScore W2386887887C2779491297 @default.
- W2386887887 hasConceptScore W2386887887C2780783641 @default.
- W2386887887 hasConceptScore W2386887887C2781466915 @default.
- W2386887887 hasConceptScore W2386887887C29730261 @default.
- W2386887887 hasConceptScore W2386887887C502032728 @default.
- W2386887887 hasConceptScore W2386887887C55493867 @default.
- W2386887887 hasConceptScore W2386887887C71924100 @default.
- W2386887887 hasConceptScore W2386887887C86803240 @default.
- W2386887887 hasConceptScore W2386887887C98274493 @default.
- W2386887887 hasLocation W23868878871 @default.
- W2386887887 hasOpenAccess W2386887887 @default.
- W2386887887 hasPrimaryLocation W23868878871 @default.
- W2386887887 hasRelatedWork W1971746999 @default.
- W2386887887 hasRelatedWork W1974038922 @default.
- W2386887887 hasRelatedWork W1977741386 @default.
- W2386887887 hasRelatedWork W2024224065 @default.
- W2386887887 hasRelatedWork W2037891478 @default.
- W2386887887 hasRelatedWork W2066344987 @default.
- W2386887887 hasRelatedWork W2089957100 @default.
- W2386887887 hasRelatedWork W2113906918 @default.
- W2386887887 hasRelatedWork W2238795172 @default.
- W2386887887 hasRelatedWork W2270273564 @default.
- W2386887887 hasRelatedWork W2364142479 @default.
- W2386887887 hasRelatedWork W2375775333 @default.
- W2386887887 hasRelatedWork W2380511768 @default.
- W2386887887 hasRelatedWork W2400918549 @default.
- W2386887887 hasRelatedWork W2412656255 @default.
- W2386887887 hasRelatedWork W2466971480 @default.
- W2386887887 hasRelatedWork W2605038284 @default.
- W2386887887 hasRelatedWork W3139223516 @default.
- W2386887887 hasRelatedWork W3140381129 @default.
- W2386887887 hasRelatedWork W3190749652 @default.
- W2386887887 isParatext "false" @default.
- W2386887887 isRetracted "false" @default.
- W2386887887 magId "2386887887" @default.
- W2386887887 workType "article" @default.