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- W2386933060 abstract "Objective To investigate antifungal effects of ethacridine against Candida Albicans in vitro.Methods Refer to NCCLSM27-A micro-dilution method,the minimal inhibitory concentration(MIC) of fluconazole alone and in combination with ethacridine was determined.The formation of hypha was induced by cultured in RPMI1640 culture medium containing 10% calf serum,and the effect of ethacridine on hyphal formation of Candida Albicans was evaluated.The ultra-structure of Candida Albicans treated with ethacridine was observed under transmission electron microscope(TEM) and scanning electron microscope(SEM).Results Candida Albicans were hypersensitive to fluconazole with the combination of ethacridine in vitro;Ethacridine could inhibit the hyphal formation and influence the synthesis of cell wall in Candida Albicans obviously.Conclusion Ethacridine have antifungal activity against Candida Albicans in vitro." @default.
- W2386933060 created "2016-06-24" @default.
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- W2386933060 date "2011-01-01" @default.
- W2386933060 modified "2023-09-27" @default.
- W2386933060 title "Antifungal effects of ethacridine against Candida Albicans in vitro" @default.
- W2386933060 hasPublicationYear "2011" @default.
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