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- W2386979894 abstract "OBJECTIVE To analyze the distribution and drug resistance of Candida causing deep fungal infections isolated from clinical specimens in order to better guide the clinical prevention and treatment of fungal infections and raise the treatment efficacy.METHODS Candida isolates were identified by Kema Jia Chromogenic Medium and ATB-ID 32C,fluconazole,5-Flucytosine,Amphotericin B,Itraconazole and Voriconazole antifungal susceptibility were tested by ATB Funguns 3,the result of the identification of Candida and the drug resistance status were analyzed.RESULTS Of 6722 clinical specimens,there were 878 strains of Candida were isolated with the detection rate of 13.06%,we performed the drug susceptibility testing for the clinically significant Candida strains including C.albicans(32.02%),C.glatraba(20.69%),C.parapsilosis(18.72%),C.tropicalis(14.29%),C.crusei(9.85%),and C.lusitaniae(2.95%);the drug susceptibility testing showed that Candida varied in the drug susceptibility to antifungal agents,the drug resistant rate of C.albicans to fluconazole was 43.08%,5-Flucytosine 40.00%,amphotericin B 32.31%,itraconazole 29.23%,voriconazole 32.31%.CONCLUSION At present,the antifungal agents for the deep fungal infections such as fluconazole,5-Flucytosine,amphotericin B,itraconazole and voriconazole have significant antibacterial activity,so it is necessary to strengthen the detection of drug resistance of Candida so as to provide basis for the reasonable use of antibiotics and reduce the drug resistance." @default.
- W2386979894 created "2016-06-24" @default.
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- W2386979894 date "2012-01-01" @default.
- W2386979894 modified "2023-09-23" @default.
- W2386979894 title "Distribution and drug resistance of common clinical Candida" @default.
- W2386979894 hasPublicationYear "2012" @default.
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