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- W2387001566 abstract "Objective To explore the association of lipopolysaccharide-binding protein(LBP) and the status of coronary artery disease(CAD).Methods Serum concentrations of LBP and high sensitivity C-reactive protein(hsCRP) were measured in 176 patients who underwent elective coronary angiography.Results Compared with 56 patients without CAD,120 with CAD showed higher LBP concentrations:12.61 mg/L vs 8.37 mg/L(P0.001).In general,a stepwise increase in plasma levels of LBP was found depending on the number of 50% coronary stenosis(P0.05) and also the atherosclerotic plaque instability(P0.01).A significant Spearman correlation was found between LBP levels and the Gensini score of coronary artery lesions(r=0.321,P0.001),and multiple stepwise regression analysis demonstrated that plasma LBP was an independent predictor of angiographic extent of CAD(β=0.180,P0.05).Conclusion Serum LBP can be used as a new serological marker of CAD indicating the vascular lesion extent and disease condition." @default.
- W2387001566 created "2016-06-24" @default.
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- W2387001566 date "2008-01-01" @default.
- W2387001566 modified "2023-09-28" @default.
- W2387001566 title "Relationship between lipopolysaccharide-binding protein and coronary artery disease" @default.
- W2387001566 hasPublicationYear "2008" @default.
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