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- W2387017845 abstract "miR-17-92 cluster is highly conserved and involved in the development of diverse organs and solid tumors in mammal.Several transcriptional factors and target genes are found,which regulated and be regulated by miR-17-92,formed some feed-forward and feed-back loops via different online databases.After functional cluster analysis of genes involved in the circus regulated by miR-17-92,the regulation network responses to miR-17-92 has been drafted out.The anlysis indicates that the jointargets of miR-17-92 and its upstream transcriptional factors may play important roles in the biological processes such as cell cycle,metastasis,apoptosis,hormone responses and the development of immune system.KEGG pathway analysis also implied that it was related to many signalling pathways in tumors.The study will be a good guideline for the further research and provide great facility for understanding the mechanism of cell development and tumorousgenesis." @default.
- W2387017845 created "2016-06-24" @default.
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- W2387017845 date "2012-03-25" @default.
- W2387017845 modified "2023-09-26" @default.
- W2387017845 title "Bioinformatics Analysis and Prediction of miR-17-92 Cluster Mediated Regulatory Network" @default.
- W2387017845 hasPublicationYear "2012" @default.
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