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- W2387052786 abstract "Objective To determine the changes of blood cytokines values and inductions of cytokines expressions after CPB and cardiac valve replacement. Methods Thirty patients undergoing cardiac valve replacement were randomly selected, The plasma cytokines levels or activities and inductions of cytokine expressions were measured before CPB, 1st, 3rd, 7th, 14th d after operation.Results Compared with the baselines, IL 1 activity and souluble interleukin 2 receptor(SIL 2R) level increased on the 1st, 3rd d , then decreased significantly on the 7th d, plasma IL 8 level increased in 14 d after CPB, but IL 2 activity decreased during 7 d postoperatively(P0.01 or 0.05), and plasma TNFα did not change markedly (P0.05); induction of IL 1 expression increased significantly on the 1st d and decreased on the 3rd d (P0.01),induction of IL 8 expression was significantly elevated on the 1st and 3rd d (P0.01), inductions of IL 2, IL 4 and SIL 2R expressions decreased significantly ofter CPB(P0.01 or 0.05), and induction of TNFα expression only decreased on the 7th d. IL 4 was not detectable during the whole procedures.Conclusions The blood cytokines values and inductions of cytokines expressions change greatly in patients after cardiac valve replacement with CPB." @default.
- W2387052786 created "2016-06-24" @default.
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- W2387052786 date "2000-01-01" @default.
- W2387052786 modified "2023-09-25" @default.
- W2387052786 title "Changes of blood cytokines values and inductions of cytokines expressions in patients after cardiac valve replacement with CPB" @default.
- W2387052786 hasPublicationYear "2000" @default.
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