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- W2387056504 abstract "Objective To explore the relationship of HER2 expression and amplification with the biology behavior of gastric carcinoma.Methods The amplification of HER2 gene and the expression of HER2 protein were detected by FISH and IHC technology respectively in 20 cases of gastric carcinoma,and the relationship between the results and clinic pathological parameters were analyzed.Results The amplification rate of HER2 gene was 35%,and the positive expression rate of HER2 protein was 30%.The positive expression of HER2 protein and the amplification of HER2 gene were associated with the depth of invasion,lymph node metastasis and clinical stage in gastric carcinoma(P0.05).Conclusion The expression of HER2 gene is correlated with invasion and metastasis of gastric carcinoma,it can be used as the index of biology behaviors and prognosis in gastric carcinoma." @default.
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- W2387056504 date "2012-01-01" @default.
- W2387056504 modified "2023-09-26" @default.
- W2387056504 title "Study on the Expression of HER-2 Gene and its Clinical Significance in Human Gastric Carcinoma" @default.
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