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- W2387116256 abstract "Objective To evaluate the effect of TCM comprehensive intervention on the mild cognitive impairment caused by leukoaraiosis.Methods Totally 78 patients with mild cognitive impairment due to leukoaraiosis were randomized into the TCM comprehensive intervention group and control group with 39 in each.The control group was treated with the regulation of life style and treatment of basic diseases,based on which,the intervention group was treated with Compound Congrong Yizhi Capsule (Herbal capsule mainly containing cistanche for cognitive impairment),4 capsules each time,3 times a day,and acupoint massage before sleep in the evening everyday.The treatment lasted for 90 days.The scores of 68 clinical symptoms,Montreal Cognitive Assessment (MoCA),and Activities of Daily Living (ADL) were used to evaluate the effect.Results After treatment,the patients in the TCM comprehensive intervention group were greatly improved in the symptoms including headache,heaviness in the head,dizziness,insomnia,restlessness,hot temper,listlessness,fatigue,palpitation,soreness and weakness in the lumbus and legs,heaviness of the body,cold extremities,thirst with desire to drink,tastelessness,cough with phlegm,shortness of breath,fullness in the chest,sighs,and hot sensation in palms and soles,with significant difference (P0.05 or P0.01).The MoCA score was increased,ADL score decreased (P0.05 or P0.01),and the score of MoCA visual space,executive function,nominating,abstract thinking,and the sub-items of delaying memory was significantly increased,with significant difference as compared with those before treatment (P0.05 or P0.01).The improvement of MoCA and ADL scores in the intervention group was more significant than that in the control group.Conclusion The TCM comprehensive intervention can improve the cognitive functions of those patients who are with cognitive impairment caused by leukoaraiosis and its induced symptoms to improve the daily living activities." @default.
- W2387116256 created "2016-06-24" @default.
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- W2387116256 date "2010-01-01" @default.
- W2387116256 modified "2023-09-26" @default.
- W2387116256 title "Effect of TCM Comprehensive Intervention on the Mild Cognitive Impairment Caused by Leukoaraiosis" @default.
- W2387116256 hasPublicationYear "2010" @default.
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