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- W2387123076 abstract "Objective To study the effects of vitamins on protection of endothelial cell impairment and serum equilibrium TXA 2 and PGI 2.Methods The animal modle of hypercholesterolemia and methionine load in rats were prepared by fed with either various vitamins as experimental groups or physiological saline as the control group for 4 weeks.The levels of serum 6-keto-prosteglandinF1α and thromboxaneB 2 which were the steady metabolites of prostacyclin and thromboxaneA 2, and the level of plasma endotheline were detected by radioimmunoassay.Results The levels of plasma endotheline and thromboxaneB 2 decreased significantly in all vitamin groups, the decrease of endotheline was more significant in the multiplex vitamin groups than that in the single vitamin group. However, we did not find significant effects of vitamins on 6-keto-prostaglandin F 1α.Conclusions The adequate supplement of vitamins is effect on protecting endothelial cell and adjusting throboxaneA 2/prostacyclin equilibrium, thereby it may be favourable for preventing atherosclerosis initiation and development." @default.
- W2387123076 created "2016-06-24" @default.
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- W2387123076 date "2002-01-01" @default.
- W2387123076 modified "2023-09-23" @default.
- W2387123076 title "Protective effect and affect of vitamins on endothelial cell and serum prostacyclin and thromboxame A_2" @default.
- W2387123076 hasPublicationYear "2002" @default.
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