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- W2387172238 abstract "Objective:Studying Bushenhuoxue prescription on premature ovarian failure (POF) of mouse follicle apoptosis-related gene expression regulation is to provide ideas for Chinese medicine of clinical prevention and treatment of premature ovarian failure.Mothods:The mouse zona pellucida 3 as the antigen,multi-point injection of subcutaneous immunization BALB/c to female mice was model of autoimmune POF.With Bushenhuoxue prescription low,medium and high-dose treatment,based Premarin as control,was detected by immunohistochemistry SABC follicle apoptosis regulatory genes (Bcl-2/Bax) protein expression.Results:Bcl-2 protein expression in the control group,Bushenhuoxue prescription of each dose groups,Premarin group were significantly higher than model group (P0.05).Bax protein expression in the control group,Bushenhuoxue prescription each of dose groups,double Premarin were significantly lower than model group (P0.05).Conclusion:Bushenhuoxue prescription may influence the apoptosis regulatory genes (Bcl-2/Bax) protein expression,regulate the immune response,inhibit antibody aggregation,inhibit abnormal follicle apoptosis,thus improving ovarian function." @default.
- W2387172238 created "2016-06-24" @default.
- W2387172238 creator A5040825774 @default.
- W2387172238 date "2010-01-01" @default.
- W2387172238 modified "2023-09-23" @default.
- W2387172238 title "Effect of Bushenhuoxue Prescription on Bcl-2/Bax Protein of Apoptosis Contress Genes in Follicle of Immune Premature Ovarian Failure Mice" @default.
- W2387172238 hasPublicationYear "2010" @default.
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