Matches in SemOpenAlex for { <https://semopenalex.org/work/W2387214896> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2387214896 abstract "Objective To establish an HPLC method for the determination of nobiletin in rat brain tissue.Methods Nobiletin in brain tissue fluid was extracted with ethyle acetate and N-hexane after precipitating by acetonitrile.Then the organic phase was evaporated to dry thoroughly with soft stream of N2,and the residues were reconstituted with the mobile phase.With nimodipine as the internal standard,the Kromasil C18 column was used(4.6 mm×150 mm,5 μm) at 40 ℃.The mobile phase consisted of methanol-water(65∶35,v/v),the flow rate was 0.8 mL·min-1 and the detective wavelength was 335 nm.Results Nobiletin was well detected apart from endogenous and the internal standard.The linear range of nobiletin brain tissue concentration was 6.25-1 200 ng·g-1(r=0.999 2),and the limit of quantification was 6.25 ng·g-1.The extraction recoveries were above 59% and the methodology recoveries were higher than 99.0%.The intra-assay and inter-assay RSD was less than 15%.Conclusion The method has good specificity,reproducibility and high sensitivity,and it can be applied to determine the nobiletin concentration in the brain tissue accurately." @default.
- W2387214896 created "2016-06-24" @default.
- W2387214896 creator A5065452686 @default.
- W2387214896 date "2010-01-01" @default.
- W2387214896 modified "2023-09-26" @default.
- W2387214896 title "Determination of nobiletin in rat brain tissue by HPLC" @default.
- W2387214896 hasPublicationYear "2010" @default.
- W2387214896 type Work @default.
- W2387214896 sameAs 2387214896 @default.
- W2387214896 citedByCount "0" @default.
- W2387214896 crossrefType "journal-article" @default.
- W2387214896 hasAuthorship W2387214896A5065452686 @default.
- W2387214896 hasConcept C119128265 @default.
- W2387214896 hasConcept C136229726 @default.
- W2387214896 hasConcept C179998833 @default.
- W2387214896 hasConcept C185592680 @default.
- W2387214896 hasConcept C2778004101 @default.
- W2387214896 hasConcept C2778401301 @default.
- W2387214896 hasConcept C2779054382 @default.
- W2387214896 hasConcept C2986936838 @default.
- W2387214896 hasConcept C43617362 @default.
- W2387214896 hasConcept C4725764 @default.
- W2387214896 hasConcept C55493867 @default.
- W2387214896 hasConcept C71924100 @default.
- W2387214896 hasConcept C95986675 @default.
- W2387214896 hasConcept C9893847 @default.
- W2387214896 hasConceptScore W2387214896C119128265 @default.
- W2387214896 hasConceptScore W2387214896C136229726 @default.
- W2387214896 hasConceptScore W2387214896C179998833 @default.
- W2387214896 hasConceptScore W2387214896C185592680 @default.
- W2387214896 hasConceptScore W2387214896C2778004101 @default.
- W2387214896 hasConceptScore W2387214896C2778401301 @default.
- W2387214896 hasConceptScore W2387214896C2779054382 @default.
- W2387214896 hasConceptScore W2387214896C2986936838 @default.
- W2387214896 hasConceptScore W2387214896C43617362 @default.
- W2387214896 hasConceptScore W2387214896C4725764 @default.
- W2387214896 hasConceptScore W2387214896C55493867 @default.
- W2387214896 hasConceptScore W2387214896C71924100 @default.
- W2387214896 hasConceptScore W2387214896C95986675 @default.
- W2387214896 hasConceptScore W2387214896C9893847 @default.
- W2387214896 hasLocation W23872148961 @default.
- W2387214896 hasOpenAccess W2387214896 @default.
- W2387214896 hasPrimaryLocation W23872148961 @default.
- W2387214896 hasRelatedWork W2038937282 @default.
- W2387214896 hasRelatedWork W2350081150 @default.
- W2387214896 hasRelatedWork W2350767337 @default.
- W2387214896 hasRelatedWork W2351198011 @default.
- W2387214896 hasRelatedWork W2352503134 @default.
- W2387214896 hasRelatedWork W2353744615 @default.
- W2387214896 hasRelatedWork W2358901608 @default.
- W2387214896 hasRelatedWork W2359566896 @default.
- W2387214896 hasRelatedWork W2362399015 @default.
- W2387214896 hasRelatedWork W2363606949 @default.
- W2387214896 hasRelatedWork W2364829259 @default.
- W2387214896 hasRelatedWork W2377494357 @default.
- W2387214896 hasRelatedWork W2378325568 @default.
- W2387214896 hasRelatedWork W2380612258 @default.
- W2387214896 hasRelatedWork W2382398198 @default.
- W2387214896 hasRelatedWork W2384118520 @default.
- W2387214896 hasRelatedWork W2385884930 @default.
- W2387214896 hasRelatedWork W2386760277 @default.
- W2387214896 hasRelatedWork W2390230453 @default.
- W2387214896 hasRelatedWork W3196415925 @default.
- W2387214896 isParatext "false" @default.
- W2387214896 isRetracted "false" @default.
- W2387214896 magId "2387214896" @default.
- W2387214896 workType "article" @default.