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- W2387250972 abstract "Objective:To study the mitochondrial respiratory function and its relation to H +ATPase activity.Methods:The liver mitochondrial respiratory control rate (RCR),phosphate/oxygen (P/O) and H + ATPase activties in endotoxic shock rats were studied.After the mitochondrion was incubated with lipopolysaccharide (LPS),changes in H +ATPase activities were also observed.Results:At the early stage of shock,the mitochondrial RCR,P/O and H +ATPase activities increase.However,they markedly decreased at the later stage of shock.The mitochondrial H +ATPase,RCR,and P/O activities were decreased after incubation with LPS in vitro.Changes in mitochondrial H +ATPase activities correlated well with RCR and P/O.Conclusions:It is suggested that the liver mitochondrial respiratory function increases at early stage while decreases at later stage,and changes in mitochondrial H +ATPase may play an important role in respiratory function during endotoxic shock." @default.
- W2387250972 created "2016-06-24" @default.
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- W2387250972 date "1999-01-01" @default.
- W2387250972 modified "2023-09-24" @default.
- W2387250972 title "Changes in liver mitochondrial H +ATPase activities in rats following endotoxic shock" @default.
- W2387250972 hasPublicationYear "1999" @default.
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