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- W2387273462 abstract "Objective: To establish a new method of isolating platelet-rich plasma(PRP) and the observation of its effects on the application in periodontal regeneration.Methods: Platelet-rich plasma was isolated by two-step centrifugation(1000r/min,15min;3000r/min,8min) from 10 adults.Then the medium was dicarded and cells were exposed to 5%,10%,30% PRP in 100μl Alpha-MEM medium to evaluate the effect of 5%,10%,30% PRP and bone graft and bone graft only in periodontal regeneration.Results: This two-step centrifugation method sequestered and concentrated platelets to a level over four times baseline whole blood.PRP and bone graft can promot periodontal regeneration.Conclusion: A convenient two-step centrifugation method of concentrating platelets is established.PRP produced by this technique and bone graft can promot periodontal regeneration and at the doses of 5%,10%,30% PRP promots periodontal regeneration in a dose-dependant manner." @default.
- W2387273462 created "2016-06-24" @default.
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- W2387273462 date "2010-01-01" @default.
- W2387273462 modified "2023-09-24" @default.
- W2387273462 title "The study of application of platelet-rich plasma in treatment of periodontal intrabony defects" @default.
- W2387273462 hasPublicationYear "2010" @default.
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