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- W2387287227 abstract "Objective To observe the impact of D-limonene on the growth of colorectal cancer in rats and on the expressions of E-cadherin (E-cad), β-catenin (β-cat) and to explore its anti-tumor mechanism from the perspective of molecular. Methods Subcutaneous injection of carcinogenic agents of DMH were used to construct the primary model of colorectal cancer, D-limonene interference was performed in the medium-term. The expression of E-cad, β-cat was observed by immunohistochemical staining. Results Abnormal expression of E-cad and β-cat was detected in both treatment and control groups. The abnormal expression rate was lower in treatment group and the ectopic expression rate of β-cat in the control group was higher. Conclusion D-limonene reduced the E-cad, β-cat abnormal expression rate and may inhibit tumor development and transfer." @default.
- W2387287227 created "2016-06-24" @default.
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- W2387287227 date "2008-01-01" @default.
- W2387287227 modified "2023-09-23" @default.
- W2387287227 title "Impact of D-limonene on the expressions of E-cadherin and β-catenin in colorectal cancer in rats" @default.
- W2387287227 hasPublicationYear "2008" @default.
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