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- W2387289993 abstract "Objective To evaluate the effect of hypertension on coronary circulation.Methods Thirty four patients with hypertension ( twenty two patients had clinical symptoms of angina pectoris with angiographically normal epicardial coronary arteries and twelve had asymptoms) were studied. Ten subjects with no cardiovascular disease served as a control group. Transesophageal coronary sinus Doppler measurements were made before and after dipyridamole administration ( 0.56 mg/ kg in 4 minutes ). Coronary flow reserve (CFR) were calculated by dividing coronary sinus flow variables after dipyridamole administration by the respective baseline values.Results CFR was significantly lower in patients with hypertension than that in control subjects ( 1.93 ± 0.55 vs 3.00 ± 0.55 ,P 0.001 ). CFR was also decreased in hypertensive patients with angina pectoris compared with that in the patients without symptoms ( 1.67 ± 0.32 vs 2.39 ± 0.58 ,P 0.001 ).Conclusions The reduction of CFR is one of the mechanism of angina pectoris outset in patients with hypertension and normal coronary arteries. Estimation of CFR by transesophageal coronary sinus Doppler measurements is feasible and reliable." @default.
- W2387289993 created "2016-06-24" @default.
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- W2387289993 date "2000-01-01" @default.
- W2387289993 modified "2023-09-24" @default.
- W2387289993 title "Evaluation of coronary flow reserve in patients with hypertension by transesophageal coronary sinus Doppler measurements" @default.
- W2387289993 hasPublicationYear "2000" @default.
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