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- W2387299399 abstract "Objective To study the effects of ZEA on estrogen receptor(ER)in rat uterine tissue and mechanism of estrogenic effects of ZEA.Methods A total of 30 rats without ovary were randomly divided into 5 groups:negative control group(distilled water),low-,mid-,and high-dose ZEA groups(0.01mg/kg,0.05mg/kg,0.20mg/kg),and positive control group(0.08mg/kg E2).Three days later,the uterine was removed.The affinity between E2 and ER,and the quantity of ER were detected using methods of radioactivity ligand bonding test and competed ER bonding test,respectively.Results Compared with negative control group,significant difference was observed in radioactivity among ZEA treatment groups(P≤0.05).Compared with negative control group,significant difference was observed in quantity of ER among ZEA treatment groups(P≥0.05).Conclusion ZEA competes ER with E2,and has affect the quantity of ER." @default.
- W2387299399 created "2016-06-24" @default.
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- W2387299399 date "2010-01-01" @default.
- W2387299399 modified "2023-09-23" @default.
- W2387299399 title "Effects of ZEA on Estrogen Receptor in Rat Uterine Tissue" @default.
- W2387299399 hasPublicationYear "2010" @default.
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