Matches in SemOpenAlex for { <https://semopenalex.org/work/W2387331567> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2387331567 abstract "Objective To investigate the difference of expression of suppressor of cytokine signaling(SOCS)(SOCS1,SOCS2,SOCS3) and cytokine-inducible SH2 containing protein 1(CIS1) in peripheral blood between polymyositis(PM) patients and healthy controls,and explore the possible roles of SOCS in the pathogenesis of PM.Methods From June to December 2001,peripheral blood samples from patients with PM(n=14) were collected and blood samples from 14 healthy adults were used as control.All the patients enrolled in this study were at active course of PM.The expression of SOCS 1-3 and CIS1 mRNA in peripheral blood leukocyte(PBL) from PM patients and healthy controls were quantified by real-time PCR analysis.Results The mRNA levels of SOCS 1-3 in PBL of PM patients were significantly lower than those in the healthy controls(P0.05).In contrast,CIS1 expression was significantly higher in PBL of PM patients in comparison with its expression in the healthy controls(P0.05).Conclusions SOCS mRNA expression levels are profoundly altered in PM patients,and SOCS cytokines may play an important role in the pathogenesis of PM.SOCS family may be a new candidate gene in the therapy of PM." @default.
- W2387331567 created "2016-06-24" @default.
- W2387331567 creator A5054871540 @default.
- W2387331567 date "2012-01-01" @default.
- W2387331567 modified "2023-09-23" @default.
- W2387331567 title "Preliminary Research on the Expression of Suppressor of Cytokine Signaling in Peripheral Blood Leukocytes of Polymyositis Patients" @default.
- W2387331567 hasPublicationYear "2012" @default.
- W2387331567 type Work @default.
- W2387331567 sameAs 2387331567 @default.
- W2387331567 citedByCount "0" @default.
- W2387331567 crossrefType "journal-article" @default.
- W2387331567 hasAuthorship W2387331567A5054871540 @default.
- W2387331567 hasConcept C121608353 @default.
- W2387331567 hasConcept C126042315 @default.
- W2387331567 hasConcept C126322002 @default.
- W2387331567 hasConcept C137061746 @default.
- W2387331567 hasConcept C14077384 @default.
- W2387331567 hasConcept C148968398 @default.
- W2387331567 hasConcept C179185449 @default.
- W2387331567 hasConcept C202751555 @default.
- W2387331567 hasConcept C203014093 @default.
- W2387331567 hasConcept C2778690821 @default.
- W2387331567 hasConcept C2779387793 @default.
- W2387331567 hasConcept C2780942790 @default.
- W2387331567 hasConcept C3017910909 @default.
- W2387331567 hasConcept C55493867 @default.
- W2387331567 hasConcept C71924100 @default.
- W2387331567 hasConcept C86803240 @default.
- W2387331567 hasConceptScore W2387331567C121608353 @default.
- W2387331567 hasConceptScore W2387331567C126042315 @default.
- W2387331567 hasConceptScore W2387331567C126322002 @default.
- W2387331567 hasConceptScore W2387331567C137061746 @default.
- W2387331567 hasConceptScore W2387331567C14077384 @default.
- W2387331567 hasConceptScore W2387331567C148968398 @default.
- W2387331567 hasConceptScore W2387331567C179185449 @default.
- W2387331567 hasConceptScore W2387331567C202751555 @default.
- W2387331567 hasConceptScore W2387331567C203014093 @default.
- W2387331567 hasConceptScore W2387331567C2778690821 @default.
- W2387331567 hasConceptScore W2387331567C2779387793 @default.
- W2387331567 hasConceptScore W2387331567C2780942790 @default.
- W2387331567 hasConceptScore W2387331567C3017910909 @default.
- W2387331567 hasConceptScore W2387331567C55493867 @default.
- W2387331567 hasConceptScore W2387331567C71924100 @default.
- W2387331567 hasConceptScore W2387331567C86803240 @default.
- W2387331567 hasLocation W23873315671 @default.
- W2387331567 hasOpenAccess W2387331567 @default.
- W2387331567 hasPrimaryLocation W23873315671 @default.
- W2387331567 hasRelatedWork W1536574418 @default.
- W2387331567 hasRelatedWork W1778858519 @default.
- W2387331567 hasRelatedWork W1992774689 @default.
- W2387331567 hasRelatedWork W2059912908 @default.
- W2387331567 hasRelatedWork W2079393295 @default.
- W2387331567 hasRelatedWork W2085262797 @default.
- W2387331567 hasRelatedWork W2140559651 @default.
- W2387331567 hasRelatedWork W2353206114 @default.
- W2387331567 hasRelatedWork W2370734673 @default.
- W2387331567 hasRelatedWork W2383786863 @default.
- W2387331567 hasRelatedWork W2407866342 @default.
- W2387331567 hasRelatedWork W2410857557 @default.
- W2387331567 hasRelatedWork W2415351432 @default.
- W2387331567 hasRelatedWork W2596512550 @default.
- W2387331567 hasRelatedWork W2944283921 @default.
- W2387331567 hasRelatedWork W3007025822 @default.
- W2387331567 hasRelatedWork W3029514595 @default.
- W2387331567 hasRelatedWork W3030635178 @default.
- W2387331567 hasRelatedWork W3030993557 @default.
- W2387331567 hasRelatedWork W3031436189 @default.
- W2387331567 isParatext "false" @default.
- W2387331567 isRetracted "false" @default.
- W2387331567 magId "2387331567" @default.
- W2387331567 workType "article" @default.