FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2387360771> ?p ?o ?g. }

• W2387360771 endingPage "1286" @default.
• W2387360771 startingPage "1283" @default.
• W2387360771 abstract "Objective To investigate the relaxative characteristics of resveratrol on thoracic aortic artery in the rat and its mechanism. Method We perfused the isolated rings and observed the response of NA-induced artery contraction to resveratrol under the Ca2+-contained and Ca2+-free bath solutions. In the same way were the effect of reveratrol on the vascular smooth muscle observed by adding two different concentration of KCl (30 and 80 mmol x L(-1)), and the effect on the contraction of the vascular smooth muscle depending on the intracellular calcium and extracellular calcium were also observed by adding NA. We also observed the effect of resveratrol on the contraction of rings induced by NA in the presence of L-NNA and Glibenclamide. Result Resveratrol relaxed rat aorta rings precontracted by NA in a dose-dependent manner. The relaxant effect of resveratrol on the rat rings of endothelium-denuded group was reduced compared with that of endothelium-intact group; the relaxant effect of resveratrol on rat rings was higher under the condition of Ca2+-free bath solution than that under the condition of Ca2+-contained bath solution. Resveratrol had a repressive effect on the aorta's contraction induced by intracellular calcium, but had no effect induced by extracellular calcium. Resveratrol relaxed the contractions induced by KCl 30 mmol x L(-1) as well as KCl 80 mmol x L(-1), but the contraction curve of KCl 80 mmol x L(-1) was shifted upward significantly. In the L-NNA group, the relaxant effect was attenuated by (26.0 +/- 4.6) %; but there was no change in the group of Glibenclamide ( P > 0.05). Conclusion The results indicate that resveratrol relaxes vascular smooth muscle in an endothelium dependent manner. The mechanisms for this phenomenon seem to be related with promoting synthesis and release of NO, opening Ca2+ activated K+ channel (KCa channel) as well as the inhibition of Ca2+ influx and release of Ca2+ from intracellular stores." @default.
• W2387360771 created "2016-06-24" @default.
• W2387360771 creator A5004807635 @default.
• W2387360771 creator A5032615847 @default.
• W2387360771 creator A5040924323 @default.
• W2387360771 creator A5062971989 @default.
• W2387360771 creator A5065784133 @default.
• W2387360771 creator A5075350471 @default.
• W2387360771 date "2005-08-01" @default.
• W2387360771 modified "2023-09-23" @default.
• W2387360771 title "Effects of resveratrol on isolated thoracic aorta rings of rats" @default.
• W2387360771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16245911" @default.
• W2387360771 hasPublicationYear "2005" @default.
• W2387360771 type Work @default.
• W2387360771 sameAs 2387360771 @default.
• W2387360771 citedByCount "3" @default.
• W2387360771 countsByYear W23873607712016 @default.
• W2387360771 countsByYear W23873607712017 @default.
• W2387360771 countsByYear W23873607712022 @default.
• W2387360771 crossrefType "journal-article" @default.
• W2387360771 hasAuthorship W2387360771A5004807635 @default.
• W2387360771 hasAuthorship W2387360771A5032615847 @default.
• W2387360771 hasAuthorship W2387360771A5040924323 @default.
• W2387360771 hasAuthorship W2387360771A5062971989 @default.
• W2387360771 hasAuthorship W2387360771A5065784133 @default.
• W2387360771 hasAuthorship W2387360771A5075350471 @default.
• W2387360771 hasConcept C105702510 @default.
• W2387360771 hasConcept C12554922 @default.
• W2387360771 hasConcept C126322002 @default.
• W2387360771 hasConcept C134018914 @default.
• W2387360771 hasConcept C163415756 @default.
• W2387360771 hasConcept C178790620 @default.
• W2387360771 hasConcept C181080969 @default.
• W2387360771 hasConcept C185592680 @default.
• W2387360771 hasConcept C2776816829 @default.
• W2387360771 hasConcept C2776864027 @default.
• W2387360771 hasConcept C2777952589 @default.
• W2387360771 hasConcept C2779395532 @default.
• W2387360771 hasConcept C2779768347 @default.
• W2387360771 hasConcept C2779980429 @default.
• W2387360771 hasConcept C28406088 @default.
• W2387360771 hasConcept C2992686903 @default.
• W2387360771 hasConcept C519063684 @default.
• W2387360771 hasConcept C55493867 @default.
• W2387360771 hasConcept C555293320 @default.
• W2387360771 hasConcept C71924100 @default.
• W2387360771 hasConcept C79879829 @default.
• W2387360771 hasConcept C84393581 @default.
• W2387360771 hasConcept C86803240 @default.
• W2387360771 hasConceptScore W2387360771C105702510 @default.
• W2387360771 hasConceptScore W2387360771C12554922 @default.
• W2387360771 hasConceptScore W2387360771C126322002 @default.
• W2387360771 hasConceptScore W2387360771C134018914 @default.
• W2387360771 hasConceptScore W2387360771C163415756 @default.
• W2387360771 hasConceptScore W2387360771C178790620 @default.
• W2387360771 hasConceptScore W2387360771C181080969 @default.
• W2387360771 hasConceptScore W2387360771C185592680 @default.
• W2387360771 hasConceptScore W2387360771C2776816829 @default.
• W2387360771 hasConceptScore W2387360771C2776864027 @default.
• W2387360771 hasConceptScore W2387360771C2777952589 @default.
• W2387360771 hasConceptScore W2387360771C2779395532 @default.
• W2387360771 hasConceptScore W2387360771C2779768347 @default.
• W2387360771 hasConceptScore W2387360771C2779980429 @default.
• W2387360771 hasConceptScore W2387360771C28406088 @default.
• W2387360771 hasConceptScore W2387360771C2992686903 @default.
• W2387360771 hasConceptScore W2387360771C519063684 @default.
• W2387360771 hasConceptScore W2387360771C55493867 @default.
• W2387360771 hasConceptScore W2387360771C555293320 @default.
• W2387360771 hasConceptScore W2387360771C71924100 @default.
• W2387360771 hasConceptScore W2387360771C79879829 @default.
• W2387360771 hasConceptScore W2387360771C84393581 @default.
• W2387360771 hasConceptScore W2387360771C86803240 @default.
• W2387360771 hasIssue "16" @default.
• W2387360771 hasLocation W23873607711 @default.
• W2387360771 hasLocation W23873607712 @default.
• W2387360771 hasOpenAccess W2387360771 @default.
• W2387360771 hasPrimaryLocation W23873607711 @default.
• W2387360771 hasRelatedWork W1966816490 @default.
• W2387360771 hasRelatedWork W1976804076 @default.
• W2387360771 hasRelatedWork W1988303163 @default.
• W2387360771 hasRelatedWork W1992362753 @default.
• W2387360771 hasRelatedWork W1994244179 @default.
• W2387360771 hasRelatedWork W2004954535 @default.
• W2387360771 hasRelatedWork W2047493483 @default.
• W2387360771 hasRelatedWork W2049624461 @default.
• W2387360771 hasRelatedWork W2053152946 @default.
• W2387360771 hasRelatedWork W2059116392 @default.
• W2387360771 hasRelatedWork W2061011934 @default.
• W2387360771 hasRelatedWork W2073974177 @default.
• W2387360771 hasRelatedWork W2078806112 @default.
• W2387360771 hasRelatedWork W2081200217 @default.
• W2387360771 hasRelatedWork W2107296859 @default.
• W2387360771 hasRelatedWork W2173797565 @default.
• W2387360771 hasRelatedWork W2183439513 @default.
• W2387360771 hasRelatedWork W2330280266 @default.
• W2387360771 hasRelatedWork W2387865079 @default.
• W2387360771 hasRelatedWork W2410021364 @default.
• W2387360771 hasVolume "30" @default.

• next