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- W2387365887 abstract "Objective:To observe the effect of intravenous fast-track anesthesia combined with epidural block in elderly patients undergoing upper abdominal operation on the plasma content of endothelin(ET)and calcitonin gene-related peptide(CGRP)in peroperative period.Methods:A total of 68 elderly patients undergoing radical gastrectomy,ASA Ⅰ-Ⅱ,were randomly divided into two groups:Group A(n=34,intravenous fast-track anesthesia)and group B(n=34,intravenous fast-track combined with epidural anesthesia).The peripheral venous blood samples were taken at different time points to test the plasma level of ET and CGRP with radioimmunoassay,and the hemodynamic changes were observed.Results:Compared with before anesthesia,the ET in both groups was decreased slightly at each time points,but no significant difference(P0.05),and there was no obvious difference in ET level between two groups(P0.05).The CGRP in both groups began to increase 5minutes after intubation,and was obviously increased5 minutes after skin incision(P0.05),and reached the peak after extubation.There was significant difference in CGRP within each group between at each time points and before surgery(P0.05).The CGRP at T2,T3 and T4time points in group A was markedly lower than that in group B(P0.05).In group B,there was obvious difference in CGRP between before anesthesia and at each time points after anesthesia(P0.05).Conclusion:The intravenous fast-track anesthesia combined with epidural block is superior to the intravenous fast-track anesthesia only for regulating the secretion of plasma ET and CGRP in elderly patients undergoing upper abdominal operation." @default.
- W2387365887 created "2016-06-24" @default.
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- W2387365887 date "2015-01-01" @default.
- W2387365887 modified "2023-09-28" @default.
- W2387365887 title "Effect of intravenous fast-track anesthesia combined with epidural block on plasma ET and TXB2 in elderly patients" @default.
- W2387365887 hasPublicationYear "2015" @default.
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