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- W2387366817 abstract "Objectives To evaluate the correlation between transforming growth factor beta 1(TGF-β1)and left ventricular hypertrophy(LVH) in patients with hypertension LVH,and amendment of left ventricular mass index(LVMI) after treated with angiotensin-converting enzyme inhibitor(ACEI) and angiotensin II receptor blockers(ARB).Methods Randomized controlled trials about TGF-β1 in patients with hypertension LVH were found by searching Medline and CNKI database.Two operants chosed suitable papers for this study.Correlation between TGF-β1 and LVH,amendment of LVMI after treated with ACEI and ARB were undertook a Meta analysis by RevMan4.3 software.Results Five papers were included in this study.Meta analysis indicated serum concentration of TGF-β1 was positively correlated with LVMI in patients with hypertension LVH,and when left ventricle function was improved by treating with ACEI and ARB,serum concentration of TGF-β1 also decreased(SMD=2.64,95% CI 2.15-3.14,P0.0001).No malignant major adverse cardiac event appeared during follow-up.Conclusions Serum concentration of TGF-β1 was positively correlated with LVMI in patients with hypertension LVH,and it may become an index to evaluate hypertension LVH." @default.
- W2387366817 created "2016-06-24" @default.
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- W2387366817 date "2011-01-01" @default.
- W2387366817 modified "2023-09-23" @default.
- W2387366817 title "Meta-analysis about transforming growth factor beta 1 in hypertension patients associated with left ventricular hypertrophy" @default.
- W2387366817 hasPublicationYear "2011" @default.
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