Matches in SemOpenAlex for { <https://semopenalex.org/work/W2387431362> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2387431362 abstract "Objective To study the effects of all-trans retinoic acid on cell proliferation and ex- pression of the cyclin E,Caspase-3 in rat C6 glioma ceils.Methods C6 glioma cells were cultured in vitro with 1,2,4,8 and 16μmol/L ATRA for 24,48,72 h respectively.The rate of inhibition was examined by MTT.The expression of cyclin E and Caspase-3 was detected by RT-PCR.Results MTT showed that ATRA could suppress the proliferation of C6 glioma cells in a dose-and time-dependent manner. There was significant difference in A values and the inhibition rate between ATRA experimental groups and control group(P＜0.01).The expression of cyclin E mRNA was down-regulated and that of Cas- pase-3 mRNA up-regulated after ATRA treatment(P＜0.01).Conclusion ATRA can inhibit the pro- liferation of rat C6 cells probably by down-regulating cyclin E and up-regulating Caspase-3 gene." @default.
- W2387431362 created "2016-06-24" @default.
- W2387431362 creator A5064592898 @default.
- W2387431362 date "2006-01-01" @default.
- W2387431362 modified "2023-09-23" @default.
- W2387431362 title "Effects of all-trans retinoic acid on expression of Cyclin E,caspase-3 in glioma cell" @default.
- W2387431362 hasPublicationYear "2006" @default.
- W2387431362 type Work @default.
- W2387431362 sameAs 2387431362 @default.
- W2387431362 citedByCount "0" @default.
- W2387431362 crossrefType "journal-article" @default.
- W2387431362 hasAuthorship W2387431362A5064592898 @default.
- W2387431362 hasConcept C104317684 @default.
- W2387431362 hasConcept C120089663 @default.
- W2387431362 hasConcept C12519072 @default.
- W2387431362 hasConcept C153911025 @default.
- W2387431362 hasConcept C185592680 @default.
- W2387431362 hasConcept C190283241 @default.
- W2387431362 hasConcept C199835354 @default.
- W2387431362 hasConcept C2778227246 @default.
- W2387431362 hasConcept C2780783641 @default.
- W2387431362 hasConcept C2781121885 @default.
- W2387431362 hasConcept C29537977 @default.
- W2387431362 hasConcept C31573885 @default.
- W2387431362 hasConcept C502942594 @default.
- W2387431362 hasConcept C55493867 @default.
- W2387431362 hasConcept C62112901 @default.
- W2387431362 hasConcept C86803240 @default.
- W2387431362 hasConcept C94561458 @default.
- W2387431362 hasConceptScore W2387431362C104317684 @default.
- W2387431362 hasConceptScore W2387431362C120089663 @default.
- W2387431362 hasConceptScore W2387431362C12519072 @default.
- W2387431362 hasConceptScore W2387431362C153911025 @default.
- W2387431362 hasConceptScore W2387431362C185592680 @default.
- W2387431362 hasConceptScore W2387431362C190283241 @default.
- W2387431362 hasConceptScore W2387431362C199835354 @default.
- W2387431362 hasConceptScore W2387431362C2778227246 @default.
- W2387431362 hasConceptScore W2387431362C2780783641 @default.
- W2387431362 hasConceptScore W2387431362C2781121885 @default.
- W2387431362 hasConceptScore W2387431362C29537977 @default.
- W2387431362 hasConceptScore W2387431362C31573885 @default.
- W2387431362 hasConceptScore W2387431362C502942594 @default.
- W2387431362 hasConceptScore W2387431362C55493867 @default.
- W2387431362 hasConceptScore W2387431362C62112901 @default.
- W2387431362 hasConceptScore W2387431362C86803240 @default.
- W2387431362 hasConceptScore W2387431362C94561458 @default.
- W2387431362 hasLocation W23874313621 @default.
- W2387431362 hasOpenAccess W2387431362 @default.
- W2387431362 hasPrimaryLocation W23874313621 @default.
- W2387431362 hasRelatedWork W1975096862 @default.
- W2387431362 hasRelatedWork W1991394667 @default.
- W2387431362 hasRelatedWork W2158712945 @default.
- W2387431362 hasRelatedWork W2348535119 @default.
- W2387431362 hasRelatedWork W2349160996 @default.
- W2387431362 hasRelatedWork W2363103717 @default.
- W2387431362 hasRelatedWork W2372588100 @default.
- W2387431362 hasRelatedWork W2372814069 @default.
- W2387431362 hasRelatedWork W2375343956 @default.
- W2387431362 hasRelatedWork W2378585145 @default.
- W2387431362 hasRelatedWork W2384358911 @default.
- W2387431362 hasRelatedWork W2388435452 @default.
- W2387431362 hasRelatedWork W2389683906 @default.
- W2387431362 hasRelatedWork W2409858545 @default.
- W2387431362 hasRelatedWork W2411337107 @default.
- W2387431362 hasRelatedWork W2418261243 @default.
- W2387431362 hasRelatedWork W2980238836 @default.
- W2387431362 hasRelatedWork W3029433168 @default.
- W2387431362 hasRelatedWork W3030587401 @default.
- W2387431362 hasRelatedWork W3029440468 @default.
- W2387431362 isParatext "false" @default.
- W2387431362 isRetracted "false" @default.
- W2387431362 magId "2387431362" @default.
- W2387431362 workType "article" @default.