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- W2387438863 abstract "[Objective] To evaluate iron store in type 2 diabetes mellitus, and to offer a new index for diagnosing iron store by measuring the value of tansferrin receptor index. [Methods] A total of 30 consecutive type 2 diabetic patients and 30 healthy subjects matched by age and gender were included in this study. sTfR concentration was determined by immunoturbidimetry and ferritin concentration was measured by electrochemiluminescence. [Results] Transferrin receptor index in T2DM was significantly lower than those in controls (P 0.01), and ferritin levels in T2DM were significantly higher than those in controls (P 0.01). However, no differences in sTfR concentrations were observed between both groups (P 0.05). A negative correlation between ferritin and sTfR concentration was detected in control subjects but not in diabetic patients (r =-0.288, P =0.03). [Conclusions] Transferrin receptor index levels in T2DM were obviously low, which indicates iron metabolic disorder. This phenomenon was caused by iron overlad. Transferrin receptor index can roundly reflect iron store." @default.
- W2387438863 created "2016-06-24" @default.
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- W2387438863 date "2007-01-01" @default.
- W2387438863 modified "2023-09-27" @default.
- W2387438863 title "Significant study on transferrin receptor index in type 2 diabetes" @default.
- W2387438863 hasPublicationYear "2007" @default.
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