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- W2387473089 abstract "Objective:The purpose of this study was to examine the changes of plasma IL-6(Interleukine-6), sIL-6R(soluble Interleukine-6 Receptor) and IL-13(Interleukine-13) in patients with first-episode schizophrenia of typeⅠand Ⅱ. Method:The plasma levels of IL-6,sIL-6R and IL-13 were measured with enzyme linked immunosorbent assay(ELISA) in 30 first-episode schizophrenics(typeⅠ=17, typeⅡ=10) and 28 normal controls. Results:Plasma levels of IL-6 and sIL-6R were significantly higher in schizophrenic patients than in normal controls (P0.05). While the IL-13 level was significantly lower in schizophrenic patients than in normal controls (P0.05).IL-6 was significantly higher in typeⅡ subgroup than in typeⅠ subgroup(P0.05).But IL-13 was markedly lower in typeⅡ than in typeⅠ (P0.05).There was no correlation among plasma levels of IL-6, sIL-6R and IL-13 in schizophrenic patients and normal controls. Conclusion:The findings suggest that schizophrenia of typeⅠand Ⅱmay result from immune dysfunction mediated through IL-6 and IL-13.Increased plasma level of IL-6 and decreased plasma level of IL-13 may be a characteristic immunological parameter for schizophrenia of typeⅡ." @default.
- W2387473089 created "2016-06-24" @default.
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- W2387473089 date "2005-01-01" @default.
- W2387473089 modified "2023-09-25" @default.
- W2387473089 title "Comparison of plasma correlative cytokine in patients with schizophrenia of type Iand II" @default.
- W2387473089 hasPublicationYear "2005" @default.
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