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- W2387489364 abstract "Objective To study the mechanism of inflammatory reaction and oxidative stress underlying the occurrence and progress of acute coronary syndrome(ACS).Methods One hundred and fourty-one patients undergoing coronary angiography were divided into control group(n=36) stable angina pectoris(SAP) group(n = 35),unstable angina pectoris(UAP) group(n = 34) and acute myocardial infarction(AMI) group(n = 36).Their serum levels of hs-CRP,IL-18 and ox-LDL were measured by ELIA.Results The serum hs-CRP,IL-18 and ox-LDL levels were significantly higher in UAP group and AMI group than in control group and SAP group,in AMI group than in UAP group(P0.05),and increased with the progress of ACS.Correlation analysis showed that the serum ox-LDL level was positively related with the serum hs-CRP and IL-18 levels after adjustment for sex,age,diabetes mellitus,hypertension and smoking(r=0.402,r =0.391,P0.01).Conclusion Inflammatory reaction and oxidative stress are involved in the occurrence and progress of ACS,which are closely related with each other.Combined detection of inflammatory reaction and oxidative stress contributes to the early diagnosis of ACS,stratification of risk,and reduction of coronary events." @default.
- W2387489364 created "2016-06-24" @default.
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- W2387489364 date "2015-01-01" @default.
- W2387489364 modified "2023-09-25" @default.
- W2387489364 title "Correlation between inflammatory reaction and oxidative stress in acute coronary syndrome" @default.
- W2387489364 hasPublicationYear "2015" @default.
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