Matches in SemOpenAlex for { <https://semopenalex.org/work/W2387508198> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2387508198 abstract "Objective To analyze the relationship between the antibiotic resistance genes and clonal complexes(CCs) of Staphylococcus aureus(S. aureus) isolates from the clinic by typing their multilocus sequence and tracing their source. Methods A total of 94S. aureus isolates were obtained and the methicillin resistant S. aureus( MRSA) were detected. Meanwhile,the antibiotic resistance genes of S. aureus,including aminoglycosides resistant genes aac(6') /aph(2''),aph(3')-Ⅲ and ant(4',4''),macrolides resistant genes ermA,ermC and msrA,and tetracyclines resistant genes tetM and tetk,were determined. CCs were analyzed with the multilocus sequence typing(MLST). Results Thirty-six MRSA isolates were detected from 94 S. aureus isolates,including 29 health care-associated MRSA(HA-MRSA) and 7 community-associated MRSA(CA-MRSA),and the former included 28 MRSA-Ⅲ and 1 MRSA-Ⅰ,while the latter included 6 MRSA-V and 1 MRSA-Ⅳd. The carrying rates of aac(6') /aph(2''),aph(3')-Ⅲ,ant(4',4''),ermA,ermC,msrA,tetM and tetk genes in 94 S. aureus isolates were 55. 3%,58. 5%,26. 6%,37. 2%,34. 0%,19. 1%,37. 2% and25. 5%,respectively. There were 35 antibiotic resistance gene profiles existed in 84 S. aureus isolates. The isolates carried with 3 or more antibiotic resistance genes accounted for 48. 9%(46 /94) of all isolates. MLST found 27 STs and 6 CCs,including 4 important clones,such as CC239,CC630,CC5 and ST398. All HA-MRSA isolates belonged to CC239,and most of CA-MRSA to CC630. There was significantly difference in carrying antibiotic resistance genes among HA-MRSA,CA-MRSA and MSSA isolates( P 0. 01) and between CC239 and the other clones(P 0. 01). Conclusion The clinical infections caused by MRSA were mainly from HA-MRSA-Ⅲ and CA-MRSA-Ⅴ. CC630 was a new clone,and ST398 was originally from human but not from animals. MRSA existed in some designated CCs,and was mainly from MSSA isolates,suggesting that thses CCs may have some special molecular structures,which may be helpful for inserting antibiotic resistance genes such as SCCmec." @default.
- W2387508198 created "2016-06-24" @default.
- W2387508198 creator A5087731980 @default.
- W2387508198 date "2014-01-01" @default.
- W2387508198 modified "2023-09-23" @default.
- W2387508198 title "Analysis on the antibiotic resistance genes and multilocus sequence typing of Staphylococcus aureus with different origins" @default.
- W2387508198 hasPublicationYear "2014" @default.
- W2387508198 type Work @default.
- W2387508198 sameAs 2387508198 @default.
- W2387508198 citedByCount "0" @default.
- W2387508198 crossrefType "journal-article" @default.
- W2387508198 hasAuthorship W2387508198A5087731980 @default.
- W2387508198 hasConcept C104317684 @default.
- W2387508198 hasConcept C135763542 @default.
- W2387508198 hasConcept C2777052132 @default.
- W2387508198 hasConcept C2777334864 @default.
- W2387508198 hasConcept C2779458865 @default.
- W2387508198 hasConcept C2779489039 @default.
- W2387508198 hasConcept C2780912031 @default.
- W2387508198 hasConcept C501593827 @default.
- W2387508198 hasConcept C515207424 @default.
- W2387508198 hasConcept C523546767 @default.
- W2387508198 hasConcept C54355233 @default.
- W2387508198 hasConcept C77434933 @default.
- W2387508198 hasConcept C86803240 @default.
- W2387508198 hasConcept C89423630 @default.
- W2387508198 hasConcept C94665300 @default.
- W2387508198 hasConceptScore W2387508198C104317684 @default.
- W2387508198 hasConceptScore W2387508198C135763542 @default.
- W2387508198 hasConceptScore W2387508198C2777052132 @default.
- W2387508198 hasConceptScore W2387508198C2777334864 @default.
- W2387508198 hasConceptScore W2387508198C2779458865 @default.
- W2387508198 hasConceptScore W2387508198C2779489039 @default.
- W2387508198 hasConceptScore W2387508198C2780912031 @default.
- W2387508198 hasConceptScore W2387508198C501593827 @default.
- W2387508198 hasConceptScore W2387508198C515207424 @default.
- W2387508198 hasConceptScore W2387508198C523546767 @default.
- W2387508198 hasConceptScore W2387508198C54355233 @default.
- W2387508198 hasConceptScore W2387508198C77434933 @default.
- W2387508198 hasConceptScore W2387508198C86803240 @default.
- W2387508198 hasConceptScore W2387508198C89423630 @default.
- W2387508198 hasConceptScore W2387508198C94665300 @default.
- W2387508198 hasOpenAccess W2387508198 @default.
- W2387508198 hasRelatedWork W2054126271 @default.
- W2387508198 hasRelatedWork W2098890661 @default.
- W2387508198 hasRelatedWork W2110730548 @default.
- W2387508198 hasRelatedWork W2150028650 @default.
- W2387508198 hasRelatedWork W2150474811 @default.
- W2387508198 hasRelatedWork W2167708689 @default.
- W2387508198 hasRelatedWork W2292621536 @default.
- W2387508198 hasRelatedWork W2352140258 @default.
- W2387508198 hasRelatedWork W2580879859 @default.
- W2387508198 hasRelatedWork W2621861347 @default.
- W2387508198 hasRelatedWork W2769311451 @default.
- W2387508198 hasRelatedWork W3000016884 @default.
- W2387508198 hasRelatedWork W3007976250 @default.
- W2387508198 hasRelatedWork W3029222095 @default.
- W2387508198 hasRelatedWork W3031622834 @default.
- W2387508198 hasRelatedWork W3033060008 @default.
- W2387508198 hasRelatedWork W3113991203 @default.
- W2387508198 hasRelatedWork W3121738822 @default.
- W2387508198 hasRelatedWork W3133903681 @default.
- W2387508198 hasRelatedWork W3209441741 @default.
- W2387508198 isParatext "false" @default.
- W2387508198 isRetracted "false" @default.
- W2387508198 magId "2387508198" @default.
- W2387508198 workType "article" @default.