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- W2387539402 abstract "Objective:To observe the mechanism of action about Shenjin mist in preventing and treating acute esophageal radioactive injury.Methods:The animal model of acute esoghageal radioactive injury in SD rats was induced by single irradiation of 43Gy gamma ray locally. Deal with all rats according to the experimental design. Investigate the changes of physiological conditions (body weight,food intake)after the rats treated with shenjin mist.And the serum levels of tumor necrosis factor-α(TNF-α),interleukin-6 (IL-6) and interleukin-1 (IL-1),the leucocyte count and different in blood,the esophageal pathological changes were detected in the experiment. Results:The animal model of acute esoghageal radioactive injury was successfully established. The experimental results manifested that leukocyte count ,lymphocyte differential count and absolute count of experimental rats were decreased after radiation,while neutrophil differential count in blood,cytokine such as TNF-α,IL-6 and IL-1 in serum increased. Compared with model group,Shenjin mist was effective in treating radiation-induced esophagitis of rats to a certain extent. Shenjin mist could improve the whole conditions,increase lymphocyte differential count and absolute count ,decrease neutrophil differential count in blood ,down-regulate the level of TNF-α,IL-6 and IL-1(P0.05). The score of esoghagus mucosa pathologic changes of high-dosage of Shenjin mist group was lower than that in model group.(P0.05).Conclusion:Shenjin mist possesses preventive and therapeutic effect on the rats with radioactive injurys of esophageal to a certain exent." @default.
- W2387539402 created "2016-06-24" @default.
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- W2387539402 date "2010-01-01" @default.
- W2387539402 modified "2023-09-24" @default.
- W2387539402 title "The Experimental Study on Shenjin Mist in Preventing and Treating Acute Esophageal Radioactive Injury" @default.
- W2387539402 hasPublicationYear "2010" @default.
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