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- W2387545439 abstract "Objective The present study was aimed to explore whether the oxidative stress was involved in the anti-atherosclerotic effect of adiponectin in patients with coronary artery disease. Methods Plasma levels of adiponectin,hemeoxygenase-1 and oxidized low density lipoprotein were determined by enzyme linked immunosorbent assay(ELISA) in 81 patients with coronary artery disease and 35 controls without coronary artery disease. Correlations were analyzed among these parameters. Results Squart-root of level of adiponectin (Sqrt adiponectin) and logarithms-transformed level of hemeoxygenase-1(ln HO-1) in patients with coronary artery disease were lower than that of controls,whereas squart-root of level of oxidized low density lipoprotein(Sqrt ox-LDL) was higher than that in the controls. Sqrt adiponectin was associated with ln HO-1 positively (r=0.617,P0.01) and Sqrt ox-LDL negatively (r=-0.556,P0.01). ln HO-1 was associated with Sqrt ox-LDL negatively (r=-0.517,P0.01). After adjustment by age,blood glucose and lipids in partial correlation analysis,Sqrt adiponectin was still associated with ln HO-1 positively (r=0.442,P0.01) and with Sqrt ox-LDL negatively (r=-0.202,P0.05). Conclusion Adiponectin was closely associated with oxidative stress and might play a role in anti-atherosclerosis by regulating oxidative stress in patients with coronary artery disease." @default.
- W2387545439 created "2016-06-24" @default.
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- W2387545439 date "2010-01-01" @default.
- W2387545439 modified "2023-09-28" @default.
- W2387545439 title "Association Between Plasma Adiponectin and Oxidative Stress in Patients with Coronary Artery Disease" @default.
- W2387545439 hasPublicationYear "2010" @default.
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