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- W2387568265 abstract "Objective To study the expressions of human β defensin-2(HBD-2) and interleukin 1β(IL-1β) in the middle ear mucosal epithelia so as to explore the effects of HBD-2 and IL-1β on the pathological process of otitis media.Methods Expressions of HBD-2 and IL-1β were detected immunohistochemically in the middle ear mucosal epithelia in chronic otitis media and in the skin of external auditory canal.Results The expressions of HBD-2 and IL-1β were significantly up-regulated in the middle ear mucosal epithelia in otitis media compared with those in the skin of normal external auditory canal(P0.05).There was a positive correlation between expressions of HBD-2 and IL-1β in the middle ear epithelial mucosa(r=0.9117,P0.05).Conclusion Expressions of HBD-2 and IL-1β in the middle ear mucosal epithelia in otitis media are both up-regulated.They may affect each other in regulating the pathological development of otitis media." @default.
- W2387568265 created "2016-06-24" @default.
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- W2387568265 date "2012-01-01" @default.
- W2387568265 modified "2023-09-24" @default.
- W2387568265 title "Expressions of human β defensin-2 and interleukin 1β in the middle ear mucosal epithelia" @default.
- W2387568265 hasPublicationYear "2012" @default.
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