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- W2387588924 abstract "Objective To discuss the distribution of abnormal chromosome karyotype in patients with acute myeloid leukemia(AML)and its clinical significance for predicting the prognosis. Methods Using R banding chromosome analysis technology,273 patients with preliminary diagnosis as having AML patients were recruited for chromosome check,and the relationship between chromosome abnormality,type of AML and prognosis was analyzed. Results Detection rate of abnormal chromosome in AML patients was 57.5%(157/273),of which,the detection rate of abnormal chromosome in MDS converted to AML was66.7%(6/9).The difference of remission rate between favourable,medium and unfavourable prognosis groups was statistically significant(χ2=16.93,P0.01). Conclusion Karyotype analysis plays an important role in the diagnosis,typing,therapy and prognosis prediction of acute myeloid leukemia." @default.
- W2387588924 created "2016-06-24" @default.
- W2387588924 creator A5078901977 @default.
- W2387588924 date "2015-01-01" @default.
- W2387588924 modified "2023-09-24" @default.
- W2387588924 title "CHROMOSOMAL CHANGE AND ITS CLINICAL SIGNIFICANCE IN PATIENTS WITH ACUTE MYELOID LEUKEMIA" @default.
- W2387588924 hasPublicationYear "2015" @default.
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