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- W2387662952 abstract "Objective To compare the antiemetic efficacy of midazolam with granisetron and normal sodium for the treatment of postoperative nausea and vomiting(PONV).Methods Ninety patients scheduled for elective gynaecological surgery under combined spinal epidural analgesia were randomized to receive intravenous midazolam 2mg in Group M,granisetron 3mg in Group G and normal saline 3ml in Group NS at the end of the surgery.Patient controlled epidural analgesia( PCEA} was maintained for remaining 48h.Results The incidence of PONV was significantly lower in Group M(32.3%) and Group G(24.1%) than that in Group NS(56.7%) in the first 24th(P0.01),but there was no statistical difference between Group M and Group G.Sedation scores was higher in Group M than those in Group G and Group NS at 2h after the surgery (P0.05).There were no significant differences in average sedation scores among the groups at 4h after the surgery.Conclusion Midazolam 2mg is as effective as granisetron 3mg in preventing PONV in patients undergoing gynaecological surgery without untoward sedative effects." @default.
- W2387662952 created "2016-06-24" @default.
- W2387662952 creator A5076531721 @default.
- W2387662952 date "2009-01-01" @default.
- W2387662952 modified "2023-09-26" @default.
- W2387662952 title "A Randomized and Double-Blind Study on the Antiemetic Efficacy of Midazolam Preventing Postoperative Nauseaand Vomiting in Patients Undergoing Gynaecological Surgery" @default.
- W2387662952 hasPublicationYear "2009" @default.
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