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- W2387667811 abstract "Purpose:To explore the classification diagnosis value and the pathological basis of hepatic angiomyolipoma(HAML) with CT and MR imaging features.Methods:The CT and MRI appearances of 21 patients with hepatic angiomyolipoma proved by pathology and clinical data were retrospectively analyzed.Results:All 21 patients were performed with helical CT scanning. Among of them,12 patients were examined by MRI. ① Angiomatous type (4 cases):Abnormal vessels were commonly seen in the lesions on pathology,which showed markedly enhancement in the early arterial phase and remained higher than the normal parenchyma in the portal phase on both CT and MR imaging features.② Myomatous type (3 cases):The myomatous type was predominantly composed of leiomyoid cells mixed with small amount of adipocytes on pathology. Hypo-density on CT plain scanning and hypo-intensity on T1 weighted imaging,higher-intensity on T2 weighted imaging were seen in these lesions,after contrast administration,marked enhanced was seen during arterial phase and marked or moderate enhanced during portal or delayed phase. ③ Lipomatous type (6 cases):Lesions of the lipomatous type were mainly composed of adipocytes which could be easily recognized on both CT and MRI.④Mixed type (9 cases):Sheets of epithelioid muscle cells admixed with islands of adipocytes and abnormal vessels were in coincident proportion composed of in the lesions,and showing in-homogeneously density on plain CT scan,mainly low signal intensity and nodular fat signal on T1 weighted imaging,in-homogeneously high signal intensity on T2 weighted imaging. On dynamic study with both CT and MRI,the soft tissues exhibited obvious enhancement,which retained to some degree during the portal phase. The melanin marker HMB45 and muscle originated marker SMA were all positive in all cases on immunohistochemical stain.Conclusion:There are significant correlation between the classification and pathological basis of hepatic angiomyolipoma at CT and MRI features. Therefore,The CT and MRI are of highly specificity for the diagnosis of HAML." @default.
- W2387667811 created "2016-06-24" @default.
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- W2387667811 date "2010-01-01" @default.
- W2387667811 modified "2023-09-23" @default.
- W2387667811 title "The Classification Diagnostic Value of CT and MRI in Hepatic Angiomyolipomas and Their Patholoical Basis" @default.
- W2387667811 hasPublicationYear "2010" @default.
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