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- W2387680213 abstract "Objective To investigate the effect of coronary vein sinus occlusion on myocardial troponinⅠ(cTnI) and fibronectin(Fn).Methods Eighteen healthy dogs were divided into control, block 1 hour and block 2 hours groups randomly.All dogs received chest open operation and coronary vein sinus was ligated at the site nearest the orifice of coronary vein sinus from epicardium. The animals were sacrificed after an hour or two hours respectively.In the control group,coronary vein sinus was not ligated.Then their hearts were taken out and samples of left ventricle were taken at same location.The immunohistochemical method was used to examine the expression of cTnI and Fn.Results Expression of cTnI and Fn of myocardium showed no significant diference after experiment compared with before.Compared with control group.expression of cTnI in block 1 hour and block 2 hours groups significantly decreased,while expression of Fn significantly increased, and the changes were more significant in bloc.2 hours group than in block 1 hour group (P 0.01).Conclusion Coronary vein sinus occlusion caused myocardial ischemic injury." @default.
- W2387680213 created "2016-06-24" @default.
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- W2387680213 date "2011-01-01" @default.
- W2387680213 modified "2023-09-23" @default.
- W2387680213 title "Immunohistochemical study of cardiac troponin I and fibronectin in dogs after block of coronary vein sinuses" @default.
- W2387680213 hasPublicationYear "2011" @default.
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